Synthesis of P-Modified DNA from Boranophosphate DNA as a Precursor via Acyl Phosphite Intermediates

[Image: see text] In this study, we successfully synthesized several kinds of P-modified nucleic acids from boranophosphate DNAs via an acyl phosphite intermediate in solution and on a solid support. In the solution-phase synthesis, phosphorothioate diester, phosphotriester, and phosphoramidate dies...

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Detalles Bibliográficos
Autores principales: Takahashi, Yuhei, Kakuta, Kiyoshi, Namioka, Yukichi, Igarashi, Ayumi, Sakamoto, Taiichi, Iwata Hara, Rintaro, Sato, Kazuki, Wada, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407935/
https://www.ncbi.nlm.nih.gov/pubmed/37462534
http://dx.doi.org/10.1021/acs.joc.3c00659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407935/
https://www.ncbi.nlm.nih.gov/pubmed/37462534
http://dx.doi.org/10.1021/acs.joc.3c00659

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