Cargando…

A crystallin mutant cataract with mineral deposits

Connexin mutant mice develop cataracts containing calcium precipitates. To test whether pathologic mineralization is a general mechanism contributing to the disease, we characterized the lenses from a nonconnexin mutant mouse cataract model. By cosegregation of the phenotype with a satellite marker...

Descripción completa

Detalles Bibliográficos
Autores principales: Minogue, Peter J., Gao, Junyuan, Mathias, Richard T., Williams, James C., Bledsoe, Sharon B., Sommer, Andre J., Beyer, Eric C., Berthoud, Viviana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407958/
https://www.ncbi.nlm.nih.gov/pubmed/37331601
http://dx.doi.org/10.1016/j.jbc.2023.104935