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Rhox6 regulates the expression of distinct target genes to mediate mouse PGCLC formation and ESC self-renewal

BACKGROUND: Mouse embryonic stem cells (mESCs) not only retain the property of self-renewal but also have the ability to develop into primordial germ cell-like cells (PGCLCs). However, knowledge about the mechanisms of transcriptional regulation is still limited. Rhox6, a member of the homeobox fami...

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Detalles Bibliográficos
Autores principales: Li, Xiaofeng, Chen, Peng, Ji, Junxiang, Duan, Quanchao, Cao, Jianjian, Huang, Ru, Ye, Shou-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10408072/
https://www.ncbi.nlm.nih.gov/pubmed/37553721
http://dx.doi.org/10.1186/s13578-023-01096-2