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Conversion of senescent cartilage into a pro-chondrogenic microenvironment with antibody-functionalized copper sulfate nanoparticles for efficient osteoarthritis therapy

The development of osteoarthritis (OA) correlates with the expansion of senescent cells in cartilage, which contributes to an inflammatory microenvironment that accelerates matrix degradation and hampers cartilage generation. To address OA, we synthesized small copper sulfide nanoparticles functiona...

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Detalles Bibliográficos
Autores principales: Wang, Xianming, Cai, Yu, Wu, Cuixi, Liang, Jiamin, Tang, Kangning, Lin, Zefeng, Chen, Lingling, Lu, Yao, Wang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10408088/
https://www.ncbi.nlm.nih.gov/pubmed/37550685
http://dx.doi.org/10.1186/s12951-023-02036-5