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Conversion of senescent cartilage into a pro-chondrogenic microenvironment with antibody-functionalized copper sulfate nanoparticles for efficient osteoarthritis therapy
The development of osteoarthritis (OA) correlates with the expansion of senescent cells in cartilage, which contributes to an inflammatory microenvironment that accelerates matrix degradation and hampers cartilage generation. To address OA, we synthesized small copper sulfide nanoparticles functiona...
Autores principales: | Wang, Xianming, Cai, Yu, Wu, Cuixi, Liang, Jiamin, Tang, Kangning, Lin, Zefeng, Chen, Lingling, Lu, Yao, Wang, Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10408088/ https://www.ncbi.nlm.nih.gov/pubmed/37550685 http://dx.doi.org/10.1186/s12951-023-02036-5 |
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