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COVPRIG robustly predicts the overall survival of IDH wild-type glioblastoma and highlights METTL1(+) neural-progenitor-like tumor cell in driving unfavorable outcome

BACKGROUND: Accurately predicting the outcome of isocitrate dehydrogenase (IDH) wild-type glioblastoma (GBM) remains hitherto challenging. This study aims to Construct and Validate a Robust Prognostic Model for IDH wild-type GBM (COVPRIG) for the prediction of overall survival using a novel metric,...

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Detalles Bibliográficos
Autores principales: Ji, Hang, Wang, Fang, Liu, Zhihui, Li, Yue, Sun, Haogeng, Xiao, Anqi, Zhang, Huanxin, You, Chao, Hu, Shaoshan, Liu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10408096/
https://www.ncbi.nlm.nih.gov/pubmed/37553713
http://dx.doi.org/10.1186/s12967-023-04382-2