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A stromal lineage maintains crypt structure and villus homeostasis in the intestinal stem cell niche
BACKGROUND: The nutrient-absorbing villi of small intestines are renewed and repaired by intestinal stem cells (ISCs), which reside in a well-organized crypt structure. Genetic studies have shown that Wnt molecules secreted by telocytes, Gli1(+) stromal cells, and epithelial cells are required for I...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10408166/ https://www.ncbi.nlm.nih.gov/pubmed/37553612 http://dx.doi.org/10.1186/s12915-023-01667-2 |