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A Sox17 downstream gene Rasip1 is involved in the hematopoietic activity of intra-aortic hematopoietic clusters in the midgestation mouse embryo

BACKGROUND: During mouse embryonic development, definitive hematopoiesis is first detected around embryonic day (E) 10.5 in the aorta-gonad-mesonephros (AGM) region. Hematopoietic stem cells (HSCs) arise in the dorsal aorta’s intra-aortic hematopoietic cell clusters (IAHCs). We have previously repor...

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Detalles Bibliográficos
Autores principales: Melig, Gerel, Nobuhisa, Ikuo, Saito, Kiyoka, Tsukahara, Ryota, Itabashi, Ayumi, Kanai, Yoshiakira, Kanai-Azuma, Masami, Osawa, Mitsujiro, Oshima, Motohiko, Iwama, Atsushi, Taga, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10408172/
https://www.ncbi.nlm.nih.gov/pubmed/37553580
http://dx.doi.org/10.1186/s41232-023-00292-4