Influenza A virus inhibits TET2 expression by endoribonuclease PA-X to attenuate type I interferon signaling and promote viral replication

Influenza A virus (IAV) expresses several accessory proteins to limit host anti-viral restriction factors to facilitate viral replication. The Ten-Eleven Translocation 2 (TET2) is a methylcytosine dioxygenase that promotes DNA demethylation by catalyzing the oxidation of 5-methylcytosine (5mC) into...

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Detalles Bibliográficos
Autores principales: Hu, Yixiang, Chen, Xinru, Ling, Yuehuan, Zhou, Kun, Han, Meiqing, Wang, Xingbo, Yue, Min, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409264/
https://www.ncbi.nlm.nih.gov/pubmed/37498975
http://dx.doi.org/10.1371/journal.ppat.1011550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409264/
https://www.ncbi.nlm.nih.gov/pubmed/37498975
http://dx.doi.org/10.1371/journal.ppat.1011550

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