Cargando…

Influenza A virus inhibits TET2 expression by endoribonuclease PA-X to attenuate type I interferon signaling and promote viral replication

Influenza A virus (IAV) expresses several accessory proteins to limit host anti-viral restriction factors to facilitate viral replication. The Ten-Eleven Translocation 2 (TET2) is a methylcytosine dioxygenase that promotes DNA demethylation by catalyzing the oxidation of 5-methylcytosine (5mC) into...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Yixiang, Chen, Xinru, Ling, Yuehuan, Zhou, Kun, Han, Meiqing, Wang, Xingbo, Yue, Min, Li, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409264/ https://www.ncbi.nlm.nih.gov/pubmed/37498975 http://dx.doi.org/10.1371/journal.ppat.1011550

Ejemplares similares

RUNX1 inhibits the antiviral immune response against influenza A virus through attenuating type I interferon signaling
por: Hu, Yixiang, et al.
Publicado: (2022)

The Influenza A Virus Endoribonuclease PA-X Usurps Host mRNA Processing Machinery to Limit Host Gene Expression
por: Gaucherand, Lea, et al.
Publicado: (2019)

Coronavirus Endoribonuclease and Deubiquitinating Interferon Antagonists Differentially Modulate the Host Response during Replication in Macrophages
por: Volk, Aaron, et al.
Publicado: (2020)

Coronavirus Endoribonuclease Ensures Efficient Viral Replication and Prevents Protein Kinase R Activation
por: Zhao, Jing, et al.
Publicado: (2021)

Inhibition of anti-viral stress granule formation by coronavirus endoribonuclease nsp15 ensures efficient virus replication
por: Gao, Bo, et al.
Publicado: (2021)

Impact of influenza PA-X on host response
por: Hayashi, Tsuyoshi, et al.
Publicado: (2015)

Influenza A Virus PA Antagonizes Interferon-β by Interacting with Interferon Regulatory Factor 3
por: Yi, Chenyang, et al.
Publicado: (2017)

PA from an H5N1 highly pathogenic avian influenza virus activates viral transcription and replication and induces apoptosis and interferon expression at an early stage of infection
por: Wang, Qiang, et al.
Publicado: (2012)

The Surface-Exposed PA(51-72)-Loop of the Influenza A Virus Polymerase Is Required for Viral Genome Replication
por: Nilsson-Payant, Benjamin E., et al.
Publicado: (2018)

Twenty amino acids at the C-terminus of PA-X are associated with increased influenza A virus replication and pathogenicity
por: Gao, Huijie, et al.
Publicado: (2015)

Inhibition of hepatitis B virus gene expression and replication by endoribonuclease-prepared siRNA
por: Meng, Zhongji, et al.
Publicado: (2008)

Porcine deltacoronavirus nsp15 antagonizes interferon-β production independently of its endoribonuclease activity
por: Liu, Xiaorong, et al.
Publicado: (2019)

Coronavirus endoribonuclease targets viral polyuridine sequences to evade activating host sensors
por: Hackbart, Matthew, et al.
Publicado: (2020)

The novel influenza A virus protein PA-X and its naturally deleted variant show different enzymatic properties in comparison to the viral endonuclease PA
por: Bavagnoli, Laura, et al.
Publicado: (2015)

Various Profiles of tet Genes Addition to tet(X) in Riemerella anatipestifer Isolates From Ducks in China
por: Zhu, De-Kang, et al.
Publicado: (2018)

Ribonuclease L and metal-ion–independent endoribonuclease cleavage sites in host and viral RNAs
por: Cooper, Daphne A., et al.
Publicado: (2014)

Inhibition of HIV-1 Viral Infection by an Engineered CRISPR Csy4 RNA Endoribonuclease
por: Guo, Rui, et al.
Publicado: (2015)

Phylogenetic Analysis of the Endoribonuclease Dicer Family
por: Gao, Zeqian, et al.
Publicado: (2014)

Substrate specificity of bacterial endoribonuclease toxins
por: Han, Yoontak, et al.
Publicado: (2020)

PA-X antagonises MAVS-dependent accumulation of early type I interferon messenger RNAs during influenza A virus infection
por: Rigby, Rachel E., et al.
Publicado: (2019)

Coronavirus Endoribonuclease Activity in Porcine Epidemic Diarrhea Virus Suppresses Type I and Type III Interferon Responses
por: Deng, Xufang, et al.
Publicado: (2019)

The N-terminal region of influenza virus polymerase PB1 adjacent to the PA binding site is involved in replication but not transcription of the viral genome
por: Binh, Nguyen Trong, et al.
Publicado: (2013)

Functional properties of the novel PA-X endonuclease of human influenza virus
por: Bavagnoli, Laura, et al.
Publicado: (2014)

Substrate specificity of human MCPIP1 endoribonuclease
por: Wilamowski, Mateusz, et al.
Publicado: (2018)

Characterization of Echinostoma cinetorchis endoribonuclease, RNase H
por: Lim, Sung-Bin, et al.
Publicado: (2017)

RNA Recognition and Cleavage by the SARS Coronavirus Endoribonuclease
por: Bhardwaj, Kanchan, et al.
Publicado: (2006)

Functional Characterization of TetR-like Transcriptional Regulator PA3973 from Pseudomonas aeruginosa
por: Kotecka, Karolina, et al.
Publicado: (2022)

An orally available, small-molecule interferon inhibits viral replication
por: Konishi, Hideyuki, et al.
Publicado: (2012)

PA28 modulates antigen processing and viral replication during coxsackievirus B3 infection
por: Respondek, Dorota, et al.
Publicado: (2017)

An anti-influenza A virus microbial metabolite acts by degrading viral endonuclease PA
por: Zhao, Jianyuan, et al.
Publicado: (2022)

Mutational and Kinetic Analysis of APE1 Endoribonuclease Activity
por: Kuznetsova, A. A., et al.
Publicado: (2021)

Reversible and irreversible inhibitors of coronavirus Nsp15 endoribonuclease
por: Chen, Jerry, et al.
Publicado: (2023)

Sporadic Dissemination of tet(X3) and tet(X6) Mediated by Highly Diverse Plasmidomes among Livestock-Associated Acinetobacter
por: Cheng, Ying-Ying, et al.
Publicado: (2021)

A novel inhibitor of monooxygenase reversed the activity of tetracyclines against tet(X3)/tet(X4)-positive bacteria
por: Xu, Lei, et al.
Publicado: (2022)

MALDI-TOF MS for rapid detection and differentiation between Tet(X)-producers and non-Tet(X)-producing tetracycline-resistant Gram-negative bacteria
por: Zheng, Zi-Jian, et al.
Publicado: (2021)

PA Mutations Inherited during Viral Evolution Act Cooperatively To Increase Replication of Contemporary H5N1 Influenza Virus with an Expanded Host Range
por: Arai, Yasuha, et al.
Publicado: (2020)

Prior upregulation of interferon pathways in the nasopharynx impacts viral shedding following live attenuated influenza vaccine challenge in children
por: Costa-Martins, André G., et al.
Publicado: (2021)

Prior upregulation of interferon pathways in the nasopharynx impacts viral shedding following live attenuated influenza vaccine challenge in children
por: Costa-Martins, André G., et al.
Publicado: (2022)

Modulation of Innate Immune Responses by the Influenza A NS1 and PA-X Proteins
por: Nogales, Aitor, et al.
Publicado: (2018)

Effects of Interferon-α/β on HBV Replication Determined by Viral Load
por: Tian, Yongjun, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_6qnaosjn3507k3m3dfhhtvq78l