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Lmo4 synergizes with Fezf2 to promote direct in vivo reprogramming of upper layer cortical neurons and cortical glia towards deep-layer neuron identities

In vivo direct neuronal reprogramming relies on the implementation of an exogenous transcriptional program allowing to achieve conversion of a particular neuronal or glial cell type towards a new identity. The transcription factor (TF) Fezf2 is known for its role in neuronal subtype specification of...

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Detalles Bibliográficos
Autores principales: Felske, Torsten, Tocco, Chiara, Péron, Sophie, Harb, Kawssar, Alfano, Christian, Galante, Chiara, Berninger, Benedikt, Studer, Michèle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409279/
https://www.ncbi.nlm.nih.gov/pubmed/37552690
http://dx.doi.org/10.1371/journal.pbio.3002237