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METTL14 reverses liver fibrosis by inhibiting NOVA2 through an m(6)A-YTHDF2–dependent mechanism

N(6)-methyladenosine (m(6)A), the most prevalent internal RNA modification in eukaryotic cells, is dynamically regulated in response to a wide range of physiological and pathological states. Nonetheless, the involvement of METTL14-induced m(6)A in liver fibrosis (LF) has yet to be established. METHO...

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Detalles Bibliográficos
Autores principales: Hou, Xiaoxue, Li, Yuwen, Song, Jiali, Peng, Linya, Zhang, Wen, Liu, Rui, Yuan, Hui, Feng, Tiantong, Li, Jieying, Li, Wenting, Zhu, Chuanlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409442/
https://www.ncbi.nlm.nih.gov/pubmed/37534933
http://dx.doi.org/10.1097/HC9.0000000000000199