TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry

SARS-CoV-2 is associated with broad tissue tropism, a characteristic often determined by the availability of entry receptors on host cells. Here, we show that TMEM106B, a lysosomal transmembrane protein, can serve as an alternative receptor for SARS-CoV-2 entry into angiotensin-converting enzyme 2 (...

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Detalles Bibliográficos
Autores principales: Baggen, Jim, Jacquemyn, Maarten, Persoons, Leentje, Vanstreels, Els, Pye, Valerie E., Wrobel, Antoni G., Calvaresi, Valeria, Martin, Stephen R., Roustan, Chloë, Cronin, Nora B., Reading, Eamonn, Thibaut, Hendrik Jan, Vercruysse, Thomas, Maes, Piet, De Smet, Frederik, Yee, Angie, Nivitchanyong, Toey, Roell, Marina, Franco-Hernandez, Natalia, Rhinn, Herve, Mamchak, Alusha Andre, Ah Young-Chapon, Maxime, Brown, Eric, Cherepanov, Peter, Daelemans, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409496/
https://www.ncbi.nlm.nih.gov/pubmed/37421949
http://dx.doi.org/10.1016/j.cell.2023.06.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409496/
https://www.ncbi.nlm.nih.gov/pubmed/37421949
http://dx.doi.org/10.1016/j.cell.2023.06.005

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