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Association of Sarcopenia with a Poor Prognosis and Decreased Tumor-Infiltrating CD8-Positive T Cells in Pancreatic Ductal Adenocarcinoma: A Retrospective Analysis

BACKGROUND: Sarcopenia, defined as a loss of skeletal muscle mass and quality, is found in 30–65% of patients with pancreatic ductal adenocarcinoma (PDAC) at diagnosis, and is a poor prognostic factor. However, it is yet to be evaluated why sarcopenia is associated with poor prognosis. Therefore, th...

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Detalles Bibliográficos
Autores principales: Masuda, Shigeto, Yamakawa, Kohei, Masuda, Atsuhiro, Toyama, Hirochika, Sofue, Keitaro, Nanno, Yoshihide, Komatsu, Shohei, Omiya, Satoshi, Sakai, Arata, Kobayashi, Takashi, Tanaka, Takeshi, Tsujimae, Masahiro, Ashina, Shigeto, Gonda, Masanori, Abe, Shohei, Uemura, Hisahiro, Kohashi, Shinya, Inomata, Noriko, Nagao, Kae, Harada, Yoshiyuki, Miki, Mika, Irie, Yosuke, Juri, Noriko, Kanzawa, Maki, Itoh, Tomoo, Fukumoto, Takumi, Kodama, Yuzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409680/
https://www.ncbi.nlm.nih.gov/pubmed/37191859
http://dx.doi.org/10.1245/s10434-023-13569-2