Temperature alters the inotropic, chronotropic and proarrhythmic effects of histamine in atrial muscle preparations from humans and H(2)-receptor overexpressing mice

We investigated whether hypothermia and hyperthermia can alter the efficacy and potency of histamine at increasing the force of cardiac contractions in mice that overexpress the human H(2) receptor only in their cardiac myocytes (labelled H(2)-TG). Contractile studies were performed in an organ bath...

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Detalles Bibliográficos
Autores principales: Hoffmann, Robert J. R., Gergs, Ulrich, Hofmann, Britt, Kirchhefer, Uwe, Neumann, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409711/
https://www.ncbi.nlm.nih.gov/pubmed/36951998
http://dx.doi.org/10.1007/s00210-023-02457-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409711/
https://www.ncbi.nlm.nih.gov/pubmed/36951998
http://dx.doi.org/10.1007/s00210-023-02457-x

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