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Temperature alters the inotropic, chronotropic and proarrhythmic effects of histamine in atrial muscle preparations from humans and H(2)-receptor overexpressing mice
We investigated whether hypothermia and hyperthermia can alter the efficacy and potency of histamine at increasing the force of cardiac contractions in mice that overexpress the human H(2) receptor only in their cardiac myocytes (labelled H(2)-TG). Contractile studies were performed in an organ bath...
Autores principales: | Hoffmann, Robert J. R., Gergs, Ulrich, Hofmann, Britt, Kirchhefer, Uwe, Neumann, Joachim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409711/ https://www.ncbi.nlm.nih.gov/pubmed/36951998 http://dx.doi.org/10.1007/s00210-023-02457-x |
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