p53 isoform expression promotes a stemness phenotype and inhibits doxorubicin sensitivity in breast cancer

In breast cancer, dysregulated TP53 expression signatures are a better predictor of chemotherapy response and survival outcomes than TP53 mutations. Our previous studies have shown that high levels of Δ40p53 are associated with worse disease-free survival and disruption of p53-induced DNA damage res...

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Detalles Bibliográficos
Autores principales: Steffens Reinhardt, Luiza, Groen, Kira, Zhang, Xiajie, Morten, Brianna C., Wawruszak, Anna, Avery-Kiejda, Kelly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409720/
https://www.ncbi.nlm.nih.gov/pubmed/37553320
http://dx.doi.org/10.1038/s41419-023-06031-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409720/
https://www.ncbi.nlm.nih.gov/pubmed/37553320
http://dx.doi.org/10.1038/s41419-023-06031-4

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