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p53 isoform expression promotes a stemness phenotype and inhibits doxorubicin sensitivity in breast cancer
In breast cancer, dysregulated TP53 expression signatures are a better predictor of chemotherapy response and survival outcomes than TP53 mutations. Our previous studies have shown that high levels of Δ40p53 are associated with worse disease-free survival and disruption of p53-induced DNA damage res...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409720/ https://www.ncbi.nlm.nih.gov/pubmed/37553320 http://dx.doi.org/10.1038/s41419-023-06031-4 |