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Carcinogenesis promotion in oral squamous cell carcinoma: KDM4A complex-mediated gene transcriptional suppression by LEF1

Oral squamous cell carcinoma (OSCC) is the most prevalent cancer of the mouth, characterised by rapid progression and poor prognosis. Hence, an urgent need exists for the development of predictive targets for early diagnosis, prognosis determination, and clinical therapy. Dysregulation of lymphoid e...

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Detalles Bibliográficos
Autores principales: Hou, Yiming, Yu, Wenqian, Wu, Gaoyi, Wang, Zhaoling, Leng, Shuai, Dong, Ming, Li, Na, Chen, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409759/
https://www.ncbi.nlm.nih.gov/pubmed/37553362
http://dx.doi.org/10.1038/s41419-023-06024-3