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Genomic dissection of endemic carbapenem resistance reveals metallo-beta-lactamase dissemination through clonal, plasmid and integron transfer

Infections caused by metallo-beta-lactamase-producing organisms (MBLs) are a global health threat. Our understanding of transmission dynamics and how MBLs establish endemicity remains limited. We analysed two decades of bla(IMP-4) evolution in a hospital using sequence data from 270 clinical and env...

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Detalles Bibliográficos
Autores principales: Macesic, Nenad, Hawkey, Jane, Vezina, Ben, Wisniewski, Jessica A., Cottingham, Hugh, Blakeway, Luke V., Harshegyi, Taylor, Pragastis, Katherine, Badoordeen, Gnei Zweena, Dennison, Amanda, Spelman, Denis W., Jenney, Adam W. J., Peleg, Anton Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409761/
https://www.ncbi.nlm.nih.gov/pubmed/37553339
http://dx.doi.org/10.1038/s41467-023-39915-2