A novel quantitative targeted analysis of X-chromosome inactivation (XCI) using nanopore sequencing

X-chromosome inactivation (XCI) analyses often assist in diagnostics of X-linked traits, however accurate assessment remains challenging with current methods. We developed a novel strategy using amplification-free Cas9 enrichment and Oxford nanopore technologies sequencing called XCI-ONT, to investi...

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Detalles Bibliográficos
Autores principales: Johansson, Josefin, Lidéus, Sarah, Höijer, Ida, Ameur, Adam, Gudmundsson, Sanna, Annerén, Göran, Bondeson, Marie-Louise, Wilbe, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409790/
https://www.ncbi.nlm.nih.gov/pubmed/37553382
http://dx.doi.org/10.1038/s41598-023-34413-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409790/
https://www.ncbi.nlm.nih.gov/pubmed/37553382
http://dx.doi.org/10.1038/s41598-023-34413-3

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