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Intradermal but not intramuscular modified vaccinia Ankara immunizations protect against intravaginal tier2 simian-human immunodeficiency virus challenges in female macaques

Route of immunization can markedly influence the quality of immune response. Here, we show that intradermal (ID) but not intramuscular (IM) modified vaccinia Ankara (MVA) vaccinations provide protection from acquisition of intravaginal tier2 simian-human immunodeficiency virus (SHIV) challenges in f...

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Detalles Bibliográficos
Autores principales: Bollimpelli, Venkata S., Reddy, Pradeep B. J, Gangadhara, Sailaja, Charles, Tysheena P., Burton, Samantha L., Tharp, Gregory K., Styles, Tiffany M., Labranche, Celia C., Smith, Justin C., Upadhyay, Amit A., Sahoo, Anusmita, Legere, Traci, Shiferaw, Ayalnesh, Velu, Vijayakumar, Yu, Tianwei, Tomai, Mark, Vasilakos, John, Kasturi, Sudhir P., Shaw, George M., Montefiori, David, Bosinger, Steven E., Kozlowski, Pamela A., Pulendran, Bali, Derdeyn, Cynthia A., Hunter, Eric, Amara, Rama R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409804/
https://www.ncbi.nlm.nih.gov/pubmed/37553348
http://dx.doi.org/10.1038/s41467-023-40430-7