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Gene expression changes in sickle cell reticulocytes and their clinical associations

Transcriptional changes in compensatory erythropoiesis in sickle cell anemia (SCA) and their disease modulation are unclear. We detected 1226 differentially expressed genes in hemoglobin SS reticulocytes compared to non-anemic hemoglobin AA controls. Assessing developmental expression changes in hem...

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Detalles Bibliográficos
Autores principales: Zhang, Xu, Song, Jihyun, Shah, Binal N., Han, Jin, Hassan, Taif, Miasniakova, Galina, Sergueeva, Adelina, Nekhai, Sergei, Machado, Roberto F., Gladwin, Mark T., Saraf, Santosh L., Prchal, Josef T., Gordeuk, Victor R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409856/
https://www.ncbi.nlm.nih.gov/pubmed/37553354
http://dx.doi.org/10.1038/s41598-023-40039-2