Modulation of translational decoding by m(6)A modification of mRNA

N(6)-methyladenosine (m(6)A) is an abundant, dynamic mRNA modification that regulates key steps of cellular mRNA metabolism. m(6)A in the mRNA coding regions inhibits translation elongation. Here, we show how m(6)A modulates decoding in the bacterial translation system using a combination of rapid k...

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Detalles Bibliográficos
Autores principales: Jain, Sakshi, Koziej, Lukasz, Poulis, Panagiotis, Kaczmarczyk, Igor, Gaik, Monika, Rawski, Michal, Ranjan, Namit, Glatt, Sebastian, Rodnina, Marina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409866/
https://www.ncbi.nlm.nih.gov/pubmed/37553384
http://dx.doi.org/10.1038/s41467-023-40422-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409866/
https://www.ncbi.nlm.nih.gov/pubmed/37553384
http://dx.doi.org/10.1038/s41467-023-40422-7

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