Cargando…

SHP2 regulates adipose maintenance and adipocyte-pancreatic cancer cell crosstalk via PDHA1

Adipocytes are the most abundant cell type in the adipose tissue, and their dysfunction is a significant driver of obesity-related pathologies, such as cancer. The mechanisms that (1) drive the maintenance and secretory activity of adipocytes and (2) mediate the cancer cellular response to the adipo...

Descripción completa

Detalles Bibliográficos
Autores principales: Olou, Appolinaire A., Ambrose, Joe, Jack, Jarrid L., Walsh, McKinnon, Ruckert, Mariana T., Eades, Austin E., Bye, Bailey A., Dandawate, Prasad, VanSaun, Michael N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409927/
https://www.ncbi.nlm.nih.gov/pubmed/36074246
http://dx.doi.org/10.1007/s12079-022-00691-1