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SHP2 regulates adipose maintenance and adipocyte-pancreatic cancer cell crosstalk via PDHA1
Adipocytes are the most abundant cell type in the adipose tissue, and their dysfunction is a significant driver of obesity-related pathologies, such as cancer. The mechanisms that (1) drive the maintenance and secretory activity of adipocytes and (2) mediate the cancer cellular response to the adipo...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409927/ https://www.ncbi.nlm.nih.gov/pubmed/36074246 http://dx.doi.org/10.1007/s12079-022-00691-1 |