Effects of CYP3A4*22 polymorphism on trough concentration of tacrolimus in kidney transplantation: a systematic review and meta-analysis

Purpose: Tacrolimus (Tac) is a widely used immunosuppressive agent in kidney transplantation. Cytochrome P450 (CYP), especially CYP3A4 enzymes are responsible for the metabolism of drugs. However, the correlation between plasma Tac concentration and CYP3A4*22 gene variants is controversial. This met...

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Detalles Bibliográficos
Autores principales: Kim, Jung Sun, Shim, Sunyoung, Yee, Jeong, Choi, Kyung Hee, Gwak, Hye Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409991/
https://www.ncbi.nlm.nih.gov/pubmed/37564175
http://dx.doi.org/10.3389/fphar.2023.1201083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409991/
https://www.ncbi.nlm.nih.gov/pubmed/37564175
http://dx.doi.org/10.3389/fphar.2023.1201083

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