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Effects of CYP3A4*22 polymorphism on trough concentration of tacrolimus in kidney transplantation: a systematic review and meta-analysis
Purpose: Tacrolimus (Tac) is a widely used immunosuppressive agent in kidney transplantation. Cytochrome P450 (CYP), especially CYP3A4 enzymes are responsible for the metabolism of drugs. However, the correlation between plasma Tac concentration and CYP3A4*22 gene variants is controversial. This met...
Autores principales: | Kim, Jung Sun, Shim, Sunyoung, Yee, Jeong, Choi, Kyung Hee, Gwak, Hye Sun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10409991/ https://www.ncbi.nlm.nih.gov/pubmed/37564175 http://dx.doi.org/10.3389/fphar.2023.1201083 |
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