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Endothelial cell telomere dysfunction induces senescence and results in vascular and metabolic impairments

In advanced age, increases in oxidative stress and inflammation impair endothelial function, which contributes to the development of cardiovascular disease (CVD). One plausible source of this oxidative stress and inflammation is an increase in the abundance of senescent endothelial cells. Cellular s...

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Detalles Bibliográficos
Autores principales: Bloom, Samuel I., Liu, Yu, Tucker, Jordan R., Islam, Md Torikul, Machin, Daniel R., Abdeahad, Hossein, Thomas, Tyler G., Bramwell, R. Colton, Lesniewski, Lisa A., Donato, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410008/
https://www.ncbi.nlm.nih.gov/pubmed/37259606
http://dx.doi.org/10.1111/acel.13875