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Endothelial cell telomere dysfunction induces senescence and results in vascular and metabolic impairments
In advanced age, increases in oxidative stress and inflammation impair endothelial function, which contributes to the development of cardiovascular disease (CVD). One plausible source of this oxidative stress and inflammation is an increase in the abundance of senescent endothelial cells. Cellular s...
Autores principales: | Bloom, Samuel I., Liu, Yu, Tucker, Jordan R., Islam, Md Torikul, Machin, Daniel R., Abdeahad, Hossein, Thomas, Tyler G., Bramwell, R. Colton, Lesniewski, Lisa A., Donato, Anthony J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410008/ https://www.ncbi.nlm.nih.gov/pubmed/37259606 http://dx.doi.org/10.1111/acel.13875 |
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