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Aberrant expression of histone deacetylase 8 in endometriosis and its potential as a therapeutic target

PURPOSE: To screen Zn(2+)‐dependent histone deacetylase (HDAC) 1‐11 in endometriotic cells and then evaluated the HDACs identified from the screening in ovarian endometrioma (OE) and deep endometriotic (DE) lesions, and to evaluate the therapeutic potential of HDAC8 inhibition in mice. METHODS: Quan...

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Detalles Bibliográficos
Autores principales: Zheng, Hanxi, Liu, Xishi, Guo, Sun‐Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410010/
https://www.ncbi.nlm.nih.gov/pubmed/37564680
http://dx.doi.org/10.1002/rmb2.12531