Endocytosis of red blood cell extracellular vesicles by macrophages leads to cytoplasmic heme release and prevents foam cell formation in atherosclerosis

Extracellular vesicles (EVs) can be produced from red blood cells (RBCs) on a large scale and used to deliver therapeutic payloads efficiently. However, not much is known about the native biological properties of RBCEVs. Here, we demonstrate that RBCEVs are primarily taken up by macrophages and mono...

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Detalles Bibliográficos
Autores principales: Pham, Thach Tuan, Le, Anh Hong, Dang, Cong Phi, Chong, Suet Yen, Do, Dang Vinh, Peng, Boya, Jayasinghe, Migara Kavishka, Ong, Hong Boon, Hoang, Dong Van, Louise, Roma Anne, Loh, Yuin‐Han, Hou, Han Wei, Wang, Jiong‐Wei, Le, Minh TN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410060/
https://www.ncbi.nlm.nih.gov/pubmed/37553837
http://dx.doi.org/10.1002/jev2.12354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410060/
https://www.ncbi.nlm.nih.gov/pubmed/37553837
http://dx.doi.org/10.1002/jev2.12354

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