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Endocytosis of red blood cell extracellular vesicles by macrophages leads to cytoplasmic heme release and prevents foam cell formation in atherosclerosis
Extracellular vesicles (EVs) can be produced from red blood cells (RBCs) on a large scale and used to deliver therapeutic payloads efficiently. However, not much is known about the native biological properties of RBCEVs. Here, we demonstrate that RBCEVs are primarily taken up by macrophages and mono...
Autores principales: | Pham, Thach Tuan, Le, Anh Hong, Dang, Cong Phi, Chong, Suet Yen, Do, Dang Vinh, Peng, Boya, Jayasinghe, Migara Kavishka, Ong, Hong Boon, Hoang, Dong Van, Louise, Roma Anne, Loh, Yuin‐Han, Hou, Han Wei, Wang, Jiong‐Wei, Le, Minh TN |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410060/ https://www.ncbi.nlm.nih.gov/pubmed/37553837 http://dx.doi.org/10.1002/jev2.12354 |
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