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Reduction of class I histone deacetylases ameliorates ER‐mitochondria cross‐talk in Alzheimer's disease

Several molecular mechanisms have been described in Alzheimer's disease (AD), including repressed gene transcription and mitochondrial and endoplasmic reticulum (ER) dysfunction. In this study, we evaluate the potential efficacy of transcriptional modifications exerted by inhibition or knockdow...

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Detalles Bibliográficos
Autores principales: Marinho, Daniela, Ferreira, Ildete Luísa, Lorenzoni, Ricardo, Cardoso, Sandra M., Santana, Isabel, Rego, A. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410063/
https://www.ncbi.nlm.nih.gov/pubmed/37358017
http://dx.doi.org/10.1111/acel.13895