Cargando…

Reduction of class I histone deacetylases ameliorates ER‐mitochondria cross‐talk in Alzheimer's disease

Several molecular mechanisms have been described in Alzheimer's disease (AD), including repressed gene transcription and mitochondrial and endoplasmic reticulum (ER) dysfunction. In this study, we evaluate the potential efficacy of transcriptional modifications exerted by inhibition or knockdow...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marinho, Daniela, Ferreira, Ildete Luísa, Lorenzoni, Ricardo, Cardoso, Sandra M., Santana, Isabel, Rego, A. Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410063/ https://www.ncbi.nlm.nih.gov/pubmed/37358017 http://dx.doi.org/10.1111/acel.13895

Ejemplares similares

Selective Inhibition of Histone Deacetylase Class IIa With MC1568 Ameliorates Podocyte Injury
por: He, Xu, et al.
Publicado: (2022)

Transcriptome analysis identifies the role of Class I histone deacetylase in Alzheimer’s disease
por: Geng, Fan, et al.
Publicado: (2023)

Class I histone deacetylases (HDAC1–3) are histone lysine delactylases
por: Moreno-Yruela, Carlos, et al.
Publicado: (2022)

Histone Deacetylases and Histone Deacetylase Inhibitors in Neuroblastoma
por: Phimmachanh, Monica, et al.
Publicado: (2020)

Transcription Regulation by Class III Histone Deacetylases (HDACs)—Sirtuins
por: Dai, Yan, et al.
Publicado: (2008)

Eloquent silence: developmental functions of Class I histone deacetylases
por: Cunliffe, Vincent T
Publicado: (2008)

Class IIa Histone Deacetylases Are Conserved Regulators of Circadian Function
por: Fogg, Paul C. M., et al.
Publicado: (2014)

A Class 1 Histone Deacetylase with Potential as an Antifungal Target
por: Bauer, Ingo, et al.
Publicado: (2016)

The class II histone deacetylases as therapeutic targets for Parkinson’s disease
por: Mazzocchi, Martina, et al.
Publicado: (2020)

Targeting Class I Histone Deacetylases in Human Uterine Leiomyosarcoma
por: Yang, Qiwei, et al.
Publicado: (2022)

The role of class IIa histone deacetylases in regulating endothelial function
por: Shen, Zexu, et al.
Publicado: (2023)

Medicinal chemistry advances in targeting class I histone deacetylases
por: Abdallah, Diaaeldin I., et al.
Publicado: (2023)

Class I histone deacetylase complex: Structure and functional correlates
por: Wang, Xiao, et al.
Publicado: (2023)

Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model
por: Dibekoğlu, Cengiz, et al.
Publicado: (2022)

Roles and Targets of Class I and IIa Histone Deacetylases in Cardiac Hypertrophy
por: Kee, Hae Jin, et al.
Publicado: (2011)

Electrocardiographic effects of class 1 selective histone deacetylase inhibitor romidepsin
por: Sager, Philip T, et al.
Publicado: (2015)

Subcellular Localization of Class I Histone Deacetylases in the Developing Xenopus tectum
por: Guo, Xia, et al.
Publicado: (2016)

Use of class I histone deacetylase inhibitor romidepsin in combination regimens
por: Petrich, Adam, et al.
Publicado: (2016)

Structure-Based Inhibitor Discovery of Class I Histone Deacetylases (HDACs)
por: Luo, Yuxiang, et al.
Publicado: (2020)

Evaluation of Class IIa Histone Deacetylases Expression and In Vivo Epigenetic Imaging in a Transgenic Mouse Model of Alzheimer’s Disease
por: Chen, Yi-An, et al.
Publicado: (2021)

Class I and Class II Histone Deacetylases Are Potential Therapeutic Targets for Treating Pancreatic Cancer
por: Wang, Guan, et al.
Publicado: (2012)

Beyond Histone and Deacetylase: An Overview of Cytoplasmic Histone Deacetylases and Their Nonhistone Substrates
por: Yao, Ya-Li, et al.
Publicado: (2011)

Histone deacetylase inhibitors mediate DNA damage repair in ameliorating hemorrhagic cystitis
por: Haldar, Subhash, et al.
Publicado: (2016)

Class IIa histone deacetylase inhibition ameliorates acute kidney injury by suppressing renal tubular cell apoptosis and enhancing autophagy and proliferation
por: Li, Jialu, et al.
Publicado: (2022)

Histone Modifications in Alzheimer’s Disease
por: Santana, Dalileia Aparecida, et al.
Publicado: (2023)

Histone deacetylase inhibitors: a new and promising drug class for the treatment of arthritis?
por: Toussirot, Éric, et al.
Publicado: (2010)

Inhibition of class II histone deacetylases in the spinal cord attenuates inflammatory hyperalgesia
por: Bai, Guang, et al.
Publicado: (2010)

The Therapeutic Potential of Class I Selective Histone Deacetylase Inhibitors in Ovarian Cancer
por: Khabele, Dineo
Publicado: (2014)

Roles and post-translational regulation of cardiac class IIa histone deacetylase isoforms
por: Weeks, Kate L, et al.
Publicado: (2015)

A distal regulatory region of a class I human histone deacetylase
por: Werbeck, Nicolas D., et al.
Publicado: (2020)

Selective Targeting of Class I Histone Deacetylases in a Model of Human Osteosarcoma
por: Torres, Haydee M., et al.
Publicado: (2021)

Class I histone deacetylases (HDAC) critically contribute to Ewing sarcoma pathogenesis
por: Schmidt, Oxana, et al.
Publicado: (2021)

Neddylation Regulates Class IIa and III Histone Deacetylases to Mediate Myoblast Differentiation
por: Zhou, Hongyi, et al.
Publicado: (2021)

Expression of Class I and Class II a/b Histone Deacetylase is Dysregulated in Hypertensive Animal Models
por: Kee, Hae Jin, et al.
Publicado: (2017)

Histone Deacetylases and Histone Deacetylase Inhibitors: Molecular Mechanisms of Action in Various Cancers
por: Sanaei, Masumeh, et al.
Publicado: (2019)

Blocking the Class I Histone Deacetylase Ameliorates Renal Fibrosis and Inhibits Renal Fibroblast Activation via Modulating TGF-Beta and EGFR Signaling
por: Liu, Na, et al.
Publicado: (2013)

Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
por: Area-Gomez, Estela, et al.
Publicado: (2012)

Histone Deacetylase Inhibitor Trichostatin A Ameliorated Endotoxin-Induced Neuroinflammation and Cognitive Dysfunction
por: Hsing, Chung-Hsi, et al.
Publicado: (2015)

Irisin Ameliorates Hypoxia/Reoxygenation-Induced Injury through Modulation of Histone Deacetylase 4
por: Zhao, Yu Tina, et al.
Publicado: (2016)

Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma
por: Ecker, Jonas, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_c011k5f40ot325qr2hprsg6i35