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Blockade of CCR1 induces a phenotypic shift in macrophages and triggers a favorable antilymphoma activity

Tumor-associated macrophages (TAMs) within the tumor microenvironment (TME) play an important role in tumor growth and progression. TAMs have been involved in producing immunosuppressive TME via various factors; however, the underlying mechanisms remain unclear in B-cell lymphoma, including mantle c...

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Detalles Bibliográficos
Autores principales: Le, Kang, Sun, Jing, Ghaemmaghami, Javid, Smith, Mitchell R., Ip, W. K. Eddie, Phillips, Tycel, Gupta, Mamta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410136/
https://www.ncbi.nlm.nih.gov/pubmed/36630565
http://dx.doi.org/10.1182/bloodadvances.2022008722