Matrix stiffness controls megakaryocyte adhesion, fibronectin fibrillogenesis, and proplatelet formation through Itgβ3

Megakaryocytes (MKs) are the precursor cells of platelets, located in the bone marrow (BM). Once mature, they extend elongated projections named proplatelets through sinusoid vessels, emerging from the marrow stroma into the circulating blood. Not all signals from the microenvironment that regulate...

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Detalles Bibliográficos
Autores principales: Guinard, Ines, Nguyen, Thao, Brassard-Jollive, Noémie, Weber, Josiane, Ruch, Laurie, Reininger, Laura, Brouard, Nathalie, Eckly, Anita, Collin, Dominique, Lanza, François, Léon, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Platelets and Thrombopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410137/
https://www.ncbi.nlm.nih.gov/pubmed/37171626
http://dx.doi.org/10.1182/bloodadvances.2022008680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410137/
https://www.ncbi.nlm.nih.gov/pubmed/37171626
http://dx.doi.org/10.1182/bloodadvances.2022008680

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