Modelling the viral dynamics of the SARS-CoV-2 Delta and Omicron variants in different cell types

We use viral kinetic models fitted to viral load data from in vitro studies to explain why the SARS-CoV-2 Omicron variant replicates faster than the Delta variant in nasal cells, but slower than Delta in lung cells, which could explain Omicron's higher transmission potential and lower severity....

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Detalles Bibliográficos
Autores principales: McCormack, Clare P., Yan, Ada W. C., Brown, Jonathan C., Sukhova, Ksenia, Peacock, Thomas P., Barclay, Wendy S., Dorigatti, Ilaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Life Sciences–Mathematics interface
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410224/
https://www.ncbi.nlm.nih.gov/pubmed/37553993
http://dx.doi.org/10.1098/rsif.2023.0187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410224/
https://www.ncbi.nlm.nih.gov/pubmed/37553993
http://dx.doi.org/10.1098/rsif.2023.0187

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