24-Hydroxycholesterol Moderates the Effects of Amyloid-β on Expression of HMG-CoA Reductase and ABCA1 Proteins in Mouse Astrocytes

BACKGROUND: Elevated brain cholesterol increases the risk of Alzheimer's disease. Production of 24-hydroxycholesterol (24s-OHC) by neurons prevents cholesterol accumulation in the brain. In this study, we investigated the effect of 24s-OHC on the HMG-COA reductase and ABCA1 which are involved i...

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Detalles Bibliográficos
Autores principales: Nazeri, Zahra, Mohammadzadeh, Ghorban, Rashidi, Mojtaba, Azizdoost, Shirin, Cheraghzadeh, Maryam, Kheirollah, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410428/
https://www.ncbi.nlm.nih.gov/pubmed/37564436
http://dx.doi.org/10.4103/abr.abr_245_22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410428/
https://www.ncbi.nlm.nih.gov/pubmed/37564436
http://dx.doi.org/10.4103/abr.abr_245_22

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