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A biomimetic approach for the concise total synthesis of greenwaylactams A–C

A concise, racemic total synthesis of three sesquiterpenoid alkaloids (greenwaylactams A–C) exhibiting an unprecedented 8-membered benzolactam is disclosed. Key transformations of this work include the ring expansion through cleavage of an indole via Witkop oxidation, as well as an HFIP mediated cat...

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Detalles Bibliográficos
Autores principales: Kratena, Nicolas, Weil, Matthias, Gärtner, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410498/
https://www.ncbi.nlm.nih.gov/pubmed/37496493
http://dx.doi.org/10.1039/d3ob01001e