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Nanopore sequencing unveils the complexity of the cold-activated murine brown adipose tissue transcriptome

Alternative transcription increases transcriptome complexity by expression of multiple transcripts per gene. Annotation and quantification of transcripts using short-read sequencing is non-trivial. Long-read sequencing aims at overcoming these problems by sequencing full-length transcripts. Activati...

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Detalles Bibliográficos
Autores principales: Engelhard, Christoph Andreas, Khani, Sajjad, Derdak, Sophia, Bilban, Martin, Kornfeld, Jan-Wilhelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410515/
https://www.ncbi.nlm.nih.gov/pubmed/37564700
http://dx.doi.org/10.1016/j.isci.2023.107190