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Crosstalk between corepressor NRIP1 and cAMP signaling on adipocyte thermogenic programming

OBJECTIVES: Nuclear receptor interacting protein 1 (NRIP1) suppresses energy expenditure via repression of nuclear receptors, and its depletion markedly elevates uncoupled respiration in mouse and human adipocytes. We tested whether NRIP1 deficient adipocytes implanted into obese mice would enhance...

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Detalles Bibliográficos
Autores principales: Tsagkaraki, Emmanouela, Guilherme, Adilson, Nicoloro, Sarah M., Kelly, Mark, Lifshitz, Lawrence M., Wang, Hui, Min, Kyounghee, Rowland, Leslie A., Santos, Kaltinaitis B., Wetoska, Nicole, Friedline, Randall H., Maitland, Stacy A., Chen, Min, Weinstein, Lee S., Wolfe, Scot A., Kim, Jason K., Czech, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410517/
https://www.ncbi.nlm.nih.gov/pubmed/37482187
http://dx.doi.org/10.1016/j.molmet.2023.101780