Polymorphic transitions in flufenamic acid-trehalose composites

The combination of poorly-soluble drugs with small molecule co-formers to generate amorphous solid dispersions (ASDs) has great potential to improve dissolution rate and kinetic solubility, and thus increase the bioavailability of these active ingredients. However, such ASDs are known to be unstable...

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Detalles Bibliográficos
Autores principales: Pang, Yuying, Gaisford, Simon, Magdysyuk, Oxana V., Williams, Gareth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410518/
https://www.ncbi.nlm.nih.gov/pubmed/37564112
http://dx.doi.org/10.1016/j.ijpx.2023.100200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410518/
https://www.ncbi.nlm.nih.gov/pubmed/37564112
http://dx.doi.org/10.1016/j.ijpx.2023.100200

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