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Polymorphic transitions in flufenamic acid-trehalose composites
The combination of poorly-soluble drugs with small molecule co-formers to generate amorphous solid dispersions (ASDs) has great potential to improve dissolution rate and kinetic solubility, and thus increase the bioavailability of these active ingredients. However, such ASDs are known to be unstable...
Autores principales: | Pang, Yuying, Gaisford, Simon, Magdysyuk, Oxana V., Williams, Gareth R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410518/ https://www.ncbi.nlm.nih.gov/pubmed/37564112 http://dx.doi.org/10.1016/j.ijpx.2023.100200 |
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