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Structure and function of a dual antagonist of the human growth hormone and prolactin receptors with site-specific PEG conjugates

Human growth hormone (hGH) is a pituitary-derived endocrine protein that regulates several critical postnatal physiologic processes including growth, organ development, and metabolism. Following adulthood, GH is also a regulator of multiple pathologies like fibrosis, cancer, and diabetes. Therefore,...

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Detalles Bibliográficos
Autores principales: Basu, Reetobrata, Brody, Rich, Sandbhor, Uday, Kulkarni, Prateek, Davis, Emily, Swegan, Deborah, Caggiano, Lydia J., Brenya, Edward, Neggers, Sebastian, Kopchick, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410519/
https://www.ncbi.nlm.nih.gov/pubmed/37442239
http://dx.doi.org/10.1016/j.jbc.2023.105030