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Structure and function of a dual antagonist of the human growth hormone and prolactin receptors with site-specific PEG conjugates
Human growth hormone (hGH) is a pituitary-derived endocrine protein that regulates several critical postnatal physiologic processes including growth, organ development, and metabolism. Following adulthood, GH is also a regulator of multiple pathologies like fibrosis, cancer, and diabetes. Therefore,...
Autores principales: | Basu, Reetobrata, Brody, Rich, Sandbhor, Uday, Kulkarni, Prateek, Davis, Emily, Swegan, Deborah, Caggiano, Lydia J., Brenya, Edward, Neggers, Sebastian, Kopchick, John J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410519/ https://www.ncbi.nlm.nih.gov/pubmed/37442239 http://dx.doi.org/10.1016/j.jbc.2023.105030 |
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