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Striatonigral distribution of a fluorescent reporter following intracerebral delivery of genome editors

Introduction: Targeted gene editing is proposed as a therapeutic approach for numerous disorders, including neurological diseases. As the brain is organized into neural networks, it is critical to understand how anatomically connected structures are affected by genome editing. For example, neurons i...

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Detalles Bibliográficos
Autores principales: Neuman, Samuel S., Metzger, Jeanette M., Bondarenko, Viktoriya, Wang, Yuyuan, Felton, Jesi, Levine, Jon E., Saha, Krishanu, Gong, Shaoqin, Emborg, Marina E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410562/
https://www.ncbi.nlm.nih.gov/pubmed/37564994
http://dx.doi.org/10.3389/fbioe.2023.1237613