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Fibroblast Activation Protein-Targeted Photodynamic Therapy of Cancer-Associated Fibroblasts in Murine Models for Pancreatic Ductal Adenocarcinoma

[Image: see text] Patients with pancreatic ductal adenocarcinoma (PDAC) have a dismal 5 year survival of 9%. One important limiting factor for treatment efficacy is the dense tumor-supporting stroma. The cancer-associated fibroblasts in this stroma deposit excessive amounts of extracellular matrix c...

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Detalles Bibliográficos
Autores principales: Dorst, Daphne N., Smeets, Esther M. M., Klein, Christian, Frielink, Cathelijne, Geijs, Daan, Trajkovic-Arsic, Marija, Cheung, Phyllis F. Y., Stommel, Martijn W. J., Gotthardt, Martin, Siveke, Jens T., Aarntzen, Erik H. J. G., van Lith, Sanne A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410663/
https://www.ncbi.nlm.nih.gov/pubmed/37485886
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00453