Mechanistic Investigation of tert-Butanol’s Impact on Biopharmaceutical Formulations: When Experiments Meet Molecular Dynamics

[Image: see text] The use of tert-butyl alcohol for the lyophilization of pharmaceuticals has seen an uptick over the past years. Its advantages include increased solubility of hydrophobic drugs, enhanced product stability, shorter reconstitution time, and decreased processing time. While the mechan...

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Detalles Bibliográficos
Autores principales: Rospiccio, Marcello, Casucci, Paola, Arsiccio, Andrea, Udrescu, Claudia, Pisano, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410665/
https://www.ncbi.nlm.nih.gov/pubmed/37435823
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410665/
https://www.ncbi.nlm.nih.gov/pubmed/37435823
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00125

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