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Structural basis for binding of Drosophila Smaug to the GPCR Smoothened and to the germline inducer Oskar

Drosophila Smaug and its orthologs comprise a family of mRNA repressor proteins that exhibit various functions during animal development. Smaug proteins contain a characteristic RNA-binding sterile-α motif (SAM) domain and a conserved but uncharacterized N-terminal domain (NTD). Here, we resolved th...

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Detalles Bibliográficos
Autores principales: Kubíková, Jana, Ubartaitė, Gabrielė, Metz, Jutta, Jeske, Mandy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410706/
https://www.ncbi.nlm.nih.gov/pubmed/37523566
http://dx.doi.org/10.1073/pnas.2304385120