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Structural basis for binding of Drosophila Smaug to the GPCR Smoothened and to the germline inducer Oskar
Drosophila Smaug and its orthologs comprise a family of mRNA repressor proteins that exhibit various functions during animal development. Smaug proteins contain a characteristic RNA-binding sterile-α motif (SAM) domain and a conserved but uncharacterized N-terminal domain (NTD). Here, we resolved th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410706/ https://www.ncbi.nlm.nih.gov/pubmed/37523566 http://dx.doi.org/10.1073/pnas.2304385120 |